human SCN10A shRNA silencing AAV

Name 
AAV-h-SCN10A-shRNA
Cat No 
shAAV-222365
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCN10A.

shAAV-222365
AAV-h-SCN10A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCN10A (sodium voltage-gated channel alpha subunit 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FEPS2; hPN3; Nav1.8; PN3; SNS
Description (Vector)
SCN10A is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy.
Gene ID
6336
Gene Name (Vector)
sodium voltage-gated channel alpha subunit 10
Gene Symbol
SCN10A
HGNC ID
HGNC:10582
ORF Size (aa)
5868
ORF Size (bp)
5868 bp
RefSeq ID
NM_006514
RefSeq Synonyms
NM_006514, NM_001293307, NM_001293306, BC172222,
Species
human
UniGene ID
Hs.250443

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.