human SCEL shRNA silencing AAV

Name 
AAV-h-SCEL-shRNA
Cat No 
shAAV-222324
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SCEL.

shAAV-222324
AAV-h-SCEL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SCEL (sciellin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
SCEL is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.
Gene ID
8796
Gene Name (Vector)
sciellin
Gene Symbol
SCEL
HGNC ID
HGNC:10573
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_003843
RefSeq Synonyms
NM_144777, NM_003843, NM_001160706, BC047536,
Species
human
UniGene ID
Hs.534699

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.