human SAA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SAA1.
shAAV-222192
AAV-h-SAA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SAA1 (serum amyloid A1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PIG4; SAA; SAA2; TP53I4
Description (Vector)
SAA1 encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
Gene ID
6288
Gene Name (Vector)
serum amyloid A1
Gene Symbol
SAA1
HGNC ID
HGNC:10513
ORF Size (aa)
369
RefSeq ID
NM_000331
RefSeq Synonyms
NM_199161, NM_001178006, NM_000331, BC105796, BC007022,
Species
human
UniGene ID
Hs.632144
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.