human RTL1 shRNA silencing AAV

Name 
AAV-h-RTL1-shRNA
Cat No 
shAAV-222085
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RTL1.

shAAV-222085
AAV-h-RTL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RTL1 (retrotransposon-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Mar1; MART1; PEG11
Description (Vector)
RTL1 is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. RTL1 is essential for maintenance of the fetal capillaries.
Gene ID
388015
Gene Name (Vector)
retrotransposon-like 1
Gene Symbol
RTL1
HGNC ID
HGNC:14665
ORF Size (aa)
4077
ORF Size (bp)
4077 bp
RefSeq ID
NM_001134888
RefSeq Synonyms
NM_001134888, BC150617,
Species
human
UniGene ID
Hs.298602

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.