human RPS11 shRNA silencing AAV

Name
AAV-h-RPS11-shRNA

Cat No
shAAV-221812

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RPS11.

shAAV-221812

AAV-h-RPS11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPS11 (ribosomal protein S11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

40S ribosomal protein S11; S11; small ribosomal subunit protein uS17

Description (eCommerce)

Ribosomal protein S11 (RPS11) a member of the S17P family of ribosomal proteins that is a component of the 40S subunit [taken from NCBI Entrez Gene (Gene ID:6205)].

Description (Vector)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.

Gene ID

6205

Gene Name (eCommerce)

ribosomal protein S11

Gene Name (Vector)

ribosomal protein S11

Gene Symbol

RPS11

HGNC ID

HGNC:10384

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

477

Protein Name (eCommerce)

40S ribosomal protein S11

RefSeq ID

NM_001015

RefSeq Synonyms

NM_001015, BC100025, BC070224, BC016378, BC010187, BC010028, BC007945, BC007603, BC007283,

Research Areas

Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,mRNA Binding,RNA Binding,RNA Processing,Signal Transduction,TNF Signaling,Translational Control

Research Areas (Faceted)

cell_biology,genetics,infectious_disease,metabolism,signal_transduction,transcription_translation

Species

human

Target Sentence

Ribosomal protein S11 (RPS11) a member of the S17P family of ribosomal proteins that is a component of the 40S subunit [taken from NCBI Entrez Gene (Gene ID:6205)].

UniGene ID

Hs.433529

UniProt ID (eCommerce)

P62280

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.