human ROPN1L shRNA silencing AAV

Name 
AAV-h-ROPN1L-shRNA
Cat No 
shAAV-221487
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ROPN1L.

shAAV-221487
AAV-h-ROPN1L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ROPN1L (rhophilin associated tail protein 1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASP; RSPH11
Description (Vector)
ROPN1L encodes a member of the ropporin family. The encoded protein is a sperm protein. It interacts with A-kinase anchoring protein, AKAP3, through the amphipathic helix region of AKAP3. Type II regulatory subunit of cAMP-dependent protein kinase (PKARII) also binds to this helix domain of AKAP3, which allows PKARII to be targeted to specific subcellular compartments. It is suggested that sperm contains several proteins that bind to AKAPs in a manner similar to PKARII, and this encoded protein may be one of them. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
83853
Gene Name (Vector)
rhophilin associated tail protein 1 like
Gene Symbol
ROPN1L
HGNC ID
HGNC:24060
ORF Size (aa)
693
RefSeq ID
NM_031916
RefSeq Synonyms
NM_031916, NM_001201466, BC014607,
Species
human
UniGene ID
Hs.381089

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.