human RILPL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RILPL1.
shAAV-221230
AAV-h-RILPL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RILPL1 (Rab interacting lysosomal protein like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GAPDH competitor of SIAH protein enhances life; GOSPEL; Rab-interacting lysosomal-like protein 1; RILP-like protein 1; RLP1
Description (eCommerce)
RILP-like protein 1, encoded for by the gene RILPL1, plays a role in the regulation of cell shape and polarity as well as cellular protein transport. RILPL1 is a neuroprotective protein - sequestering GAPDH in the cytosol thereby preventing the apoptotic function of GAPDH in the nucleus [taken from UniProtKB (Entry: Q5EBL4)].
Gene ID
353116
Gene Name (eCommerce)
Rab interacting lysosomal protein like 1
Gene Name (Vector)
Rab interacting lysosomal protein like 1
Gene Symbol
RILPL1
HGNC ID
HGNC:26814
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
ORF Size (bp)
759 bp
Protein Name (eCommerce)
RILP-like protein 1
RefSeq ID
NM_178314
RefSeq Synonyms
NM_178314, NM_001319302, NM_001319244, NM_001319243, BC089444, BC080626,
Research Areas
Apoptosis,Cytoskeleton,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
RILP-like protein 1, encoded for by the gene RILPL1, plays a role in the regulation of cell shape and polarity as well as cellular protein transport. RILPL1 is a neuroprotective protein - sequestering GAPDH in the cytosol thereby preventing the apoptotic function of GAPDH in the nucleus [taken from UniProtKB (Entry: Q5EBL4)].
UniGene ID
Hs.530315
UniProt ID (eCommerce)
Q5EBL4
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.