human RGS12 shRNA silencing AAV

Name 
AAV-h-RGS12-shRNA
Cat No 
shAAV-221111
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RGS12.

shAAV-221111
AAV-h-RGS12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGS12 (regulator of G-protein signaling 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
RGS12 encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.
Gene ID
6002
Gene Name (Vector)
regulator of G-protein signaling 12
Gene Symbol
RGS12
HGNC ID
HGNC:9994
ORF Size (aa)
4344
ORF Size (bp)
4344 bp
RefSeq ID
NM_002926
RefSeq Synonyms
NM_198229, NM_198227, NM_002926, BC167850,
Species
human
UniGene ID
Hs.527061

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.