human RGMA shRNA silencing AAV

Name
AAV-h-RGMA-shRNA

Cat No
shAAV-221093

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RGMA.

shAAV-221093

AAV-h-RGMA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGMA (repulsive guidance molecule family member a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGM

Description (Vector)

RGMA encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants.

Gene ID

56963

Gene Name (Vector)

repulsive guidance molecule family member a

Gene Symbol

RGMA

HGNC ID

HGNC:30308

ORF Size (aa)

1350

ORF Size (bp)

1350 bp

RefSeq ID

NM_020211

RefSeq Synonyms

NM_020211, NM_001166289, NM_001166288, NM_001166287, NM_001166286, NM_001166283, BC151132, BC146682, BC140838,

Species

human

UniGene ID

Hs.271277

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.