human RFX2 shRNA silencing AAV

Name
AAV-h-RFX2-shRNA

Cat No
shAAV-221067

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RFX2.

shAAV-221067

AAV-h-RFX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RFX2 (regulatory factor X2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

RFX2 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

Gene ID

5990

Gene Name (Vector)

regulatory factor X2

Gene Symbol

RFX2

HGNC ID

HGNC:9983

ORF Size (aa)

2172

ORF Size (bp)

2172 bp

RefSeq ID

NM_000635

RefSeq Synonyms

NM_134433, NM_000635, BC071571, BC028579,

Species

human

UniGene ID

Hs.465709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.