human RFWD3 shRNA silencing AAV

Name 
AAV-h-RFWD3-shRNA
Cat No 
shAAV-221065
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RFWD3.

shAAV-221065
AAV-h-RFWD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RFWD3 (ring finger and WD repeat domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase RFWD3; FANCW; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; RING-type E3 ubiquitin transferase RFWD3; RNF201
Description (eCommerce)
RFWD3 (ring finger and WD repeat domain 3) has been identified as a protein that is phosphorylated in response to DNA damage. The exact function of RFWD3 (ring finger and WD repeat domain 3) has not been characterized. Structurally, RFWD3 possesses a RING-type zinc finger and 3 WD repeats.
Gene ID
55159
Gene Name (eCommerce)
ring finger and WD repeat domain 3
Gene Name (Vector)
ring finger and WD repeat domain 3
Gene Symbol
RFWD3
HGNC ID
HGNC:25539
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2325
ORF Size (bp)
2325 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RFWD3
RefSeq ID
NM_018124
RefSeq Synonyms
NM_018124, BC059371,
Research Areas
Cell Cycle,DNA Damage/Repair,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
RFWD3 (ring finger and WD repeat domain 3) has been identified as a protein that is phosphorylated in response to DNA damage. The exact function of RFWD3 (ring finger and WD repeat domain 3) has not been characterized. Structurally, RFWD3 possesses a RING-type zinc finger and 3 WD repeats.
UniGene ID
Hs.567525
UniProt ID (eCommerce)
Q6PCD5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.