human RELB shRNA silencing AAV

Name
AAV-h-RELB-shRNA

Cat No
shAAV-220996

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RELB.

shAAV-220996

AAV-h-RELB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RELB (RELB proto-oncogene, NF-kB subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IMD53; IREL; I-REL; REL-B; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Description (eCommerce)

The members of the Rel family bear a characteristic 300 amino acid N-terminal Rel homology domain (RHD). The Rel members include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The Rel proteins combine as heterodimers or homodimers to form the NF-kappa B transcription factor which functions to mediate pleiotropic cellular effects in response to injury, infection and stress.

Gene ID

5971

Gene Name (eCommerce)

RELB proto-oncogene, NF-kB subunit

Gene Name (Vector)

RELB proto-oncogene, NF-kB subunit

Gene Symbol

RELB

HGNC ID

HGNC:9956

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1740

ORF Size (bp)

1740 bp

Protein Name (eCommerce)

Transcription factor RelB

RefSeq ID

NM_006509

RefSeq Synonyms

NM_006509, BC028013,

Research Areas

Antigen Processing and Presentation,Cytoskeleton,DNA Damage/Repair,Gene Expression,Host-Virus Interactions,Immunology,Interleukin Signaling,MAPK Signaling,NF-kB Signaling,RANKL-RANK Signaling,Signal Transduction,TNF Signaling,Transcription Factor/Regulator,TSLP Signaling,TWEAK Signaling

Research Areas (Faceted)

signal_transduction,immunology,cell_biology,genetics,transcription_translation,infectious_disease,immunology,signal_transduction,genetics,transcription_translation,signal_transduction

Species

human

Target Sentence

The members of the Rel family bear a characteristic 300 amino acid N-terminal Rel homology domain (RHD). The Rel members include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The Rel proteins combine as heterodimers or homodimers to form the NF-kappa B transcription factor which functions to mediate pleiotropic cellular effects in response to injury, infection and stress.

UniGene ID

Hs.654402

UniProt ID (eCommerce)

Q01201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.