human RBPJL shRNA silencing AAV

Name
AAV-h-RBPJL-shRNA

Cat No
shAAV-220924

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RBPJL.

shAAV-220924

AAV-h-RBPJL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RBPJL (recombination signal binding protein for immunoglobulin kappa J region like). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RBPL; RBPSUHL; SUHL

Description (Vector)

In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

Gene ID

11317

Gene Name (Vector)

recombination signal binding protein for immunoglobulin kappa J region like

Gene Symbol

RBPJL

HGNC ID

HGNC:13761

ORF Size (aa)

1554

ORF Size (bp)

1554 bp

RefSeq ID

NM_014276

RefSeq Synonyms

NM_014276, NM_001281449, NM_001281448, BC156875, BC152895,

Species

human

UniGene ID

Hs.248217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.