human RASSF8 shRNA silencing AAV

Name
AAV-h-RASSF8-shRNA

Cat No
shAAV-220812

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RASSF8.

shAAV-220812

AAV-h-RASSF8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RASSF8 (Ras association domain family member 8). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C12orf2; HOJ1

Description (Vector)

RASSF8 encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. RASSF8 is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

11228

Gene Name (Vector)

Ras association domain family member 8

Gene Symbol

RASSF8

HGNC ID

HGNC:13232

ORF Size (aa)

1179

ORF Size (bp)

1179 bp

RefSeq ID

NM_007211

RefSeq Synonyms

NM_007211, NM_001164748, NM_001164747, NM_001164746, BC030021,

Species

human

UniGene ID

Hs.696433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.