human RASGRP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RASGRP2.
shAAV-220780
AAV-h-RASGRP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RASGRP2 (RAS guanyl releasing protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CALDAG-GEFI; CDC25L
Description (Vector)
RASGRP2 is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
10235
Gene Name (Vector)
RAS guanyl releasing protein 2
Gene Symbol
RASGRP2
HGNC ID
HGNC:9879
ORF Size (aa)
1830
ORF Size (bp)
1830 bp
RefSeq ID
NM_001098671
RefSeq Synonyms
NM_153819, NM_001318398, NM_001098671, NM_001098670, BC117151,
Species
human
UniGene ID
Hs.99491
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.