human RARG shRNA silencing AAV

Name
AAV-h-RARG-shRNA

Cat No
shAAV-220749

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RARG.

shAAV-220749

AAV-h-RARG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RARG (retinoic acid receptor gamma). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NR1B3; RARC

Description (Vector)

RARG encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

5916

Gene Name (Vector)

retinoic acid receptor gamma

Gene Symbol

RARG

HGNC ID

HGNC:9866

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_000966

RefSeq Synonyms

NM_001243732, NM_001243731, NM_001243730, NM_001042728, NM_000966, BC093729, BC093727,

Species

human

UniGene ID

Hs.1497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.