human QPCT shRNA silencing AAV

Name 
AAV-h-QPCT-shRNA
Cat No 
shAAV-220467
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human QPCT.

shAAV-220467
AAV-h-QPCT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human QPCT (glutaminyl-peptide cyclotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GCT; QC; sQC
Description (Vector)
QPCT encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.
Gene ID
25797
Gene Name (Vector)
glutaminyl-peptide cyclotransferase
Gene Symbol
QPCT
HGNC ID
HGNC:9753
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
RefSeq ID
NM_012413
RefSeq Synonyms
NM_012413, BC047756, BC036721,
Species
human
UniGene ID
Hs.79033

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.