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human PTPRD shRNA silencing AAV

Name 
AAV-h-PTPRD-shRNA
Cat No 
shAAV-220341
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTPRD.

shAAV-220341
AAV-h-PTPRD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTPRD (protein tyrosine phosphatase, receptor type D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
77
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA
Description (Vector)
PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
Gene ID
5789
Gene Name (Vector)
protein tyrosine phosphatase, receptor type D
Gene Symbol
PTPRD
HGNC ID
HGNC:9668
ORF Size (aa)
4491
ORF Size (bp)
4491 bp
RefSeq ID
NM_002839
RefSeq Synonyms
NM_130393, NM_130392, NM_130391, NM_002839, NM_001171025, NM_001040712, BC106716, BC106715, BC106714, BC106713,
Species
human
UniGene ID
Hs.446083

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.