human PTPN23 shRNA silencing AAV

Name 
AAV-h-PTPN23-shRNA
Cat No 
shAAV-220321
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTPN23.

shAAV-220321
AAV-h-PTPN23-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTPN23 (protein tyrosine phosphatase, non-receptor type 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HDPTP; HD-PTP; his domain-containing protein tyrosine phosphatase; protein tyrosine phosphatase TD14; PTP-TD14; tyrosine-protein phosphatase non-receptor type 23
Description (eCommerce)
His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3S7].
Gene ID
25930
Gene Name (eCommerce)
protein tyrosine phosphatase, non-receptor type 23
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 23
Gene Symbol
PTPN23
HGNC ID
HGNC:14406
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4911
ORF Size (bp)
4911 bp
Protein Name (eCommerce)
Tyrosine-protein phosphatase non-receptor type 23
RefSeq ID
NM_015466
RefSeq Synonyms
NM_015466, NM_001304482, BC089042,
Research Areas
Cytoskeleton,EGFR Signaling,Kinase/Phosphatase,Phosphatase,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3S7].
UniGene ID
Hs.25524
UniProt ID (eCommerce)
Q9H3S7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.