human PTPN14 shRNA silencing AAV

Name 
AAV-h-PTPN14-shRNA
Cat No 
shAAV-220311
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTPN14.

shAAV-220311
AAV-h-PTPN14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTPN14 (protein tyrosine phosphatase, non-receptor type 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PEZ; PTP36
Description (Vector)
PTPN14 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
Gene ID
5784
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 14
Gene Symbol
PTPN14
HGNC ID
HGNC:9647
ORF Size (aa)
3564
ORF Size (bp)
3564 bp
RefSeq ID
NM_005401
RefSeq Synonyms
NM_005401, BC104803, BC101754,
Species
human
UniGene ID
Hs.696573

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.