human PTP4A3 shRNA silencing AAV

Name 
AAV-h-PTP4A3-shRNA
Cat No 
shAAV-220299
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTP4A3.

shAAV-220299
AAV-h-PTP4A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTP4A3 (protein tyrosine phosphatase type IVA, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PRL-3; PRL-R; PRL3
Description (Vector)
PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.
Gene ID
11156
Gene Name (Vector)
protein tyrosine phosphatase type IVA, member 3
Gene Symbol
PTP4A3
HGNC ID
HGNC:9636
ORF Size (aa)
447
RefSeq ID
NM_007079
RefSeq Synonyms
NM_032611, NM_007079, BC003105,
Species
human
UniGene ID
Hs.43666

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.