human PSMD14 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PSMD14.
shAAV-220154
AAV-h-PSMD14-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PSMD14 (proteasome 26S subunit, non-ATPase 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
26S proteasome non-ATPase regulatory subunit 14; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated PAD1 homolog 1; PAD1; POH1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; RPN11; testis tissue sperm-binding protein Li 69n
Description (eCommerce)
PSMD14 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 14] is a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. PSMD14 is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination [taken from NCBI Entrez Gene (Gene ID: 10213)].
Description (Vector)
PSMD14 encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.
Gene ID
10213
Gene Name (eCommerce)
proteasome 26S subunit, non-ATPase 14
Gene Name (Vector)
proteasome 26S subunit, non-ATPase 14
Gene Symbol
PSMD14
HGNC ID
HGNC:16889
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
933
Protein Name (eCommerce)
26S proteasome non-ATPase regulatory subunit 14
RefSeq ID
NM_005805
RefSeq Synonyms
NM_005805, BC066336,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cell Cycle,Cell Division,Complexome,DNA Damage/Repair,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,Neurobiology,Neurodegeneration,Parkinson's Disease,Parkin-Ubiquitin Proteasomal System,Proteasome,RNA Processing,Ubiquitination
Research Areas (Faceted)
cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism,neurobiology,cell_biology
Species
human
Target Sentence
PSMD14 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 14] is a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. PSMD14 is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination [taken from NCBI Entrez Gene (Gene ID: 10213)].
UniGene ID
Hs.567410
UniProt ID (eCommerce)
O00487
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.