human PSMD10 shRNA silencing AAV

Name
AAV-h-PSMD10-shRNA

Cat No
shAAV-220147

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PSMD10.

shAAV-220147

AAV-h-PSMD10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PSMD10 (proteasome 26S subunit, non-ATPase 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ889N15.2; p28; p28(GANK)

Description (Vector)

PSMD10 encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Gene ID

5716

Gene Name (Vector)

proteasome 26S subunit, non-ATPase 10

Gene Symbol

PSMD10

HGNC ID

HGNC:9555

ORF Size (aa)

681

RefSeq ID

NM_002814

RefSeq Synonyms

NM_170750, NM_002814, BC011960,

Species

human

UniGene ID

Hs.522752

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.