human PRPS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PRPS1.
shAAV-219967
AAV-h-PRPS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PRPS1 (phosphoribosyl pyrophosphate synthetase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRS-I; PRSI
Description (Vector)
PRPS1 encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
5631
Gene Name (Vector)
phosphoribosyl pyrophosphate synthetase 1
Gene Symbol
PRPS1
HGNC ID
HGNC:9462
ORF Size (aa)
957
RefSeq ID
NM_002764
RefSeq Synonyms
NM_002764, NM_001204402, BC001605,
Species
human
UniGene ID
Hs.56
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.