human PROK2 shRNA silencing AAV

Name 
AAV-h-PROK2-shRNA
Cat No 
shAAV-219929
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PROK2.

shAAV-219929
AAV-h-PROK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PROK2 (prokineticin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BV8; HH4; KAL4; MIT1; PK2
Description (Vector)
PROK2 encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
60675
Gene Name (Vector)
prokineticin 2
Gene Symbol
PROK2
HGNC ID
HGNC:18455
ORF Size (aa)
390
RefSeq ID
NM_021935
RefSeq Synonyms
NM_021935, NM_001126128, BC098162, BC098110, BC096695, BC069395,
Species
human
UniGene ID
Hs.528665

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.