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human PRKAG2 shRNA silencing AAV

Name 
AAV-h-PRKAG2-shRNA
Cat No 
shAAV-219846
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRKAG2.

shAAV-219846
AAV-h-PRKAG2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AAKG; AAKG2; CMH6; H91620p; WPWS
Description (Vector)
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
51422
Gene Name (Vector)
protein kinase AMP-activated non-catalytic subunit gamma 2
Gene Symbol
PRKAG2
HGNC ID
HGNC:9386
ORF Size (aa)
1578
ORF Size (bp)
1578 bp
RefSeq ID
NM_016203
RefSeq Synonyms
NM_024429, NM_016203, NM_001304531, NM_001304527, NM_001040633, BC068598, BC020540,
Species
human
UniGene ID
Hs.647072

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.