human PREX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PREX1.
shAAV-219808
AAV-h-PREX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
P-REX1
Description (Vector)
PREX1 acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Gene ID
57580
Gene Name (Vector)
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
Gene Symbol
PREX1
HGNC ID
HGNC:32594
ORF Size (aa)
4977
ORF Size (bp)
4977 bp
RefSeq ID
NM_020820
RefSeq Synonyms
NM_020820, BC156402,
Species
human
UniGene ID
Hs.153310
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.