human POP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POP1.
shAAV-219446
AAV-h-POP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POP1 (POP1 homolog, ribonuclease P/MRP subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
POP1 encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.
Gene ID
10940
Gene Name (Vector)
POP1 homolog, ribonuclease P/MRP subunit
Gene Symbol
POP1
HGNC ID
HGNC:30129
ORF Size (aa)
3075
ORF Size (bp)
3075 bp
RefSeq ID
NM_015029
RefSeq Synonyms
NM_015029, NM_001145861, NM_001145860, BC011529,
Species
human
UniGene ID
Hs.252828
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.