human PON1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PON1.
shAAV-219442
AAV-h-PON1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PON1 (paraoxonase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ESA; MVCD5; PON
Description (Vector)
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
Gene ID
5444
Gene Name (Vector)
paraoxonase 1
Gene Symbol
PON1
HGNC ID
HGNC:9204
ORF Size (aa)
1068
RefSeq ID
NM_000446
RefSeq Synonyms
NM_000446, BC074719,
Species
human
UniGene ID
Hs.370995
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.