human POLR1C shRNA silencing AAV

Name
AAV-h-POLR1C-shRNA

Cat No
shAAV-219380

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human POLR1C.

shAAV-219380

AAV-h-POLR1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POLR1C (RNA polymerase I subunit C). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AC40; HLD11; RPA39; RPA40; RPA5; RPAC1; RPC40; TCS3

Description (Vector)

POLR1C is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS).

Gene ID

9533

Gene Name (Vector)

RNA polymerase I subunit C

Gene Symbol

POLR1C

HGNC ID

HGNC:20194

ORF Size (aa)

1041

ORF Size (bp)

1041 bp

RefSeq ID

NM_203290

RefSeq Synonyms

NM_203290, NM_001318876, BC008863,

Species

human

UniGene ID

Hs.584839

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.