human PLIN shRNA silencing AAV

Name 
AAV-h-PLIN-shRNA
Cat No 
shAAV-219209
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PLIN1.

shAAV-219209
AAV-h-PLIN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLIN1 (perilipin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FPLD4; PERI; PLIN
Description (Vector)
PLIN1 coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.
Gene ID
5346
Gene Name (Vector)
perilipin 1
Gene Symbol
PLIN1
HGNC ID
HGNC:9076
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_002666
RefSeq Synonyms
NM_002666, NM_001145311, BC031084,
Species
human
UniGene ID
Hs.103253

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.