human PLCB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLCB1.
shAAV-219116
AAV-h-PLCB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLCB1 (phospholipase C beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIEE12; PI-PLC; PLC-154; PLC-beta-1; PLC-I; PLC154; PLCB1A; PLCB1B
Description (Vector)
PLCB1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
23236
Gene Name (Vector)
phospholipase C beta 1
Gene Symbol
PLCB1
HGNC ID
HGNC:15917
ORF Size (aa)
3522
ORF Size (bp)
3522 bp
RefSeq ID
NM_182734
RefSeq Synonyms
NM_182734, NM_015192, BC117231, BC069420,
Species
human
UniGene ID
Hs.431173
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.