human PLA2G1B shRNA silencing AAV

Name
AAV-h-PLA2G1B-shRNA

Cat No
shAAV-219063

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PLA2G1B.

shAAV-219063

AAV-h-PLA2G1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLA2G1B (phospholipase A2 group IB). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PLA2; PLA2A; PPLA2

Description (Vector)

Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 (PubMed 3028739)) .(supplied by OMIM, Mar 2008)

Gene ID

5319

Gene Name (Vector)

phospholipase A2 group IB

Gene Symbol

PLA2G1B

HGNC ID

HGNC:9030

ORF Size (aa)

447

RefSeq ID

NM_000928

RefSeq Synonyms

NM_000928, BC106726, BC106725, BC005386,

Species

human

UniGene ID

Hs.992

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.