human PLA2G15 shRNA silencing AAV

Name 
AAV-h-PLA2G15-shRNA
Cat No 
shAAV-219060
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PLA2G15.

shAAV-219060
AAV-h-PLA2G15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLA2G15 (phospholipase A2 group XV). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACS; GXVPLA2; LLPL; LPLA2; LYPLA3
Description (Vector)
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
Gene ID
23659
Gene Name (Vector)
phospholipase A2 group XV
Gene Symbol
PLA2G15
HGNC ID
HGNC:17163
ORF Size (aa)
1239
ORF Size (bp)
1239 bp
RefSeq ID
NM_012320
RefSeq Synonyms
NM_012320, BC062605, BC011640,
Species
human
UniGene ID
Hs.632199

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.