human PKN3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PKN3.
shAAV-219042
AAV-h-PKN3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PKN3 (protein kinase N3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
protein kinase PKN-beta; protein-kinase C-related kinase 3; serine/threonine-protein kinase N3; UTDP4-1
Description (eCommerce)
Protein kinase N3 is a serine/threonine protein kinase and one of three PKN isoforms (PKN1, PKN2, PKN3) encoded by independent genes. PKN3 has been identified as an effector that mediates malignant prostate cell growth and is activated by PI3-kinase.
Gene ID
29941
Gene Name (eCommerce)
protein kinase N3
Gene Name (Vector)
protein kinase N3
Gene Symbol
PKN3
HGNC ID
HGNC:17999
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2670
ORF Size (bp)
2670 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase N3
RefSeq ID
NM_013355
RefSeq Synonyms
NM_013355, NM_001317926, BC062558,
Research Areas
Golgi Apparatus,Kinase/Phosphatase,PI3K/Akt Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Protein kinase N3 is a serine/threonine protein kinase and one of three PKN isoforms (PKN1, PKN2, PKN3) encoded by independent genes. PKN3 has been identified as an effector that mediates malignant prostate cell growth and is activated by PI3-kinase.
UniGene ID
Hs.300485
UniProt ID (eCommerce)
Q6P5Z2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.