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human PKN2 shRNA silencing AAV

Name 
AAV-h-PKN2-shRNA
Cat No 
shAAV-219041
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PKN2.

shAAV-219041
AAV-h-PKN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PKN2 (protein kinase N2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cardiolipin-activated protein kinase Pak2; PAK2; Pak-2; PKN gamma; PRK2; PRKCL2; PRO2042; protein kinase C-like 2; protein-kinase C-related kinase 2; serine/threonine-protein kinase N2; STK7
Description (eCommerce)
Protein kinase N2 (PKN2) is a Ser/Thr kinase and Rho/Rac effector protein. PKN2 has been shown to phosphorylate and activate Cdc25B and control entry into mitosis and exit from cytokinesis.
Gene ID
5586
Gene Name (eCommerce)
protein kinase N2
Gene Name (Vector)
protein kinase N2
Gene Symbol
PKN2
HGNC ID
HGNC:9406
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2811
ORF Size (bp)
2811 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase N2
RefSeq ID
NM_006256
RefSeq Synonyms
NM_006256, NM_001320709, NM_001320708, NM_001320707, BC125199,
Research Areas
Apoptosis,Cell Cycle,Cell Division,Cytoskeleton,EGFR Signaling,Immunology,Kinase/Phosphatase,PI3K/Akt Signaling,Rho Signaling,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,immunology,cell_biology,signal_transduction,genetics,transcription_translation
Species
human
Target Sentence
Protein kinase N2 (PKN2) is a Ser/Thr kinase and Rho/Rac effector protein. PKN2 has been shown to phosphorylate and activate Cdc25B and control entry into mitosis and exit from cytokinesis.
UniGene ID
Hs.440833
UniProt ID (eCommerce)
Q16513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.