human PITPNM3 shRNA silencing AAV

Name
AAV-h-PITPNM3-shRNA

Cat No
shAAV-218998

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PITPNM3.

shAAV-218998

AAV-h-PITPNM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PITPNM3 (PITPNM family member 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACKR6; CORD5; NIR1; RDGBA3

Description (Vector)

PITPNM3 encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

83394

Gene Name (Vector)

PITPNM family member 3

Gene Symbol

PITPNM3

HGNC ID

HGNC:21043

ORF Size (aa)

2925

ORF Size (bp)

2925 bp

RefSeq ID

NM_031220

RefSeq Synonyms

NM_031220, NM_001165966, BC128584, BC128583,

Species

human

UniGene ID

Hs.183983

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.