human PIP5K1C shRNA silencing AAV

Name 
AAV-h-PIP5K1C-shRNA
Cat No 
shAAV-218985
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PIP5K1C.

shAAV-218985
AAV-h-PIP5K1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma
Description (Vector)
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
23396
Gene Name (Vector)
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
Gene Symbol
PIP5K1C
HGNC ID
HGNC:8996
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_012398
RefSeq Synonyms
NM_012398, NM_001300849, NM_001195733, BC167798,
Species
human
UniGene ID
Hs.282177

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.