human PIK3R6 shRNA silencing AAV

Name
AAV-h-PIK3R6-shRNA

Cat No
shAAV-218964

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PIK3R6.

shAAV-218964

AAV-h-PIK3R6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIK3R6 (phosphoinositide-3-kinase regulatory subunit 6). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C17orf38; HsT41028; p84 PIKAP; p87(PIKAP); p87PIKAP

Description (Vector)

Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors.

Gene ID

146850

Gene Name (Vector)

phosphoinositide-3-kinase regulatory subunit 6

Gene Symbol

PIK3R6

HGNC ID

HGNC:27101

ORF Size (aa)

2265

ORF Size (bp)

2265 bp

RefSeq ID

NM_001010855

RefSeq Synonyms

NM_001290211, NM_001010855, BC166645,

Species

human

UniGene ID

Hs.255809

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.