human PIK3CG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIK3CG.
shAAV-218952
AAV-h-PIK3CG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Description (Vector)
PIK3CG encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Gene ID
5294
Gene Name (Vector)
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Gene Symbol
PIK3CG
HGNC ID
HGNC:8978
ORF Size (aa)
3309
ORF Size (bp)
3309 bp
RefSeq ID
NM_002649
RefSeq Synonyms
NM_002649, NM_001282427, NM_001282426, BC035683,
Species
human
UniGene ID
Hs.32942
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.