human PIGN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIGN.
shAAV-218914
AAV-h-PIGN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIGN (phosphatidylinositol glycan anchor biosynthesis class N). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCAHS; MCAHS1; MCD4; MDC4; PIG-N
Description (Vector)
PIGN encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported.
Gene ID
23556
Gene Name (Vector)
phosphatidylinositol glycan anchor biosynthesis class N
Gene Symbol
PIGN
HGNC ID
HGNC:8967
ORF Size (aa)
2796
ORF Size (bp)
2796 bp
RefSeq ID
NM_012327
RefSeq Synonyms
NM_176787, NM_012327, BC028363,
Species
human
UniGene ID
Hs.157031
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.