human PICK1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PICK1.
shAAV-218898
AAV-h-PICK1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PICK1 (protein interacting with PRKCA 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PICK; PRKCABP
Description (Vector)
PICK1 contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
9463
Gene Name (Vector)
protein interacting with PRKCA 1
Gene Symbol
PICK1
HGNC ID
HGNC:9394
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_012407
RefSeq Synonyms
NM_012407, NM_001039584, NM_001039583, BC017561,
Species
human
UniGene ID
Hs.180871
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.