human PHEX shRNA silencing AAV

Name
AAV-h-PHEX-shRNA

Cat No
shAAV-218793

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PHEX.

shAAV-218793

AAV-h-PHEX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PHEX (phosphate regulating endopeptidase homolog, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HPDR; HPDR1; HYP; HYP1; LXHR; PEX; XLH

Description (Vector)

PHEX is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets.

Gene ID

5251

Gene Name (Vector)

phosphate regulating endopeptidase homolog, X-linked

Gene Symbol

PHEX

HGNC ID

HGNC:8918

ORF Size (aa)

2250

ORF Size (bp)

2250 bp

RefSeq ID

NM_000444

RefSeq Synonyms

NM_001282754, NM_000444, BC105059, BC105057,

Species

human

UniGene ID

Hs.495834

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.