human PGDS shRNA silencing AAV

Name
AAV-h-PGDS-shRNA

Cat No
shAAV-218730

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HPGDS.

shAAV-218730

AAV-h-PGDS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HPGDS (hematopoietic prostaglandin D synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GSTS; GSTS1; GSTS1-1; PGD2; PGDS

Description (Vector)

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.

Gene ID

27306

Gene Name (Vector)

hematopoietic prostaglandin D synthase

Gene Symbol

HPGDS

HGNC ID

HGNC:17890

ORF Size (aa)

600

RefSeq ID

NM_014485

RefSeq Synonyms

NM_014485, BC020734,

Species

human

UniGene ID

Hs.128433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.