human PFKFB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PFKFB3.
shAAV-218678
AAV-h-PFKFB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6PF-2-K/Fru-2,6-P2ase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; IPFK2; iPFK-2; PFK/FBPase 3; PFK2; renal carcinoma antigen NY-REN-56
Description (eCommerce)
PFKFB3 is involved in the synthesis and degradation of fructose 2,6-bisphosphate [taken from NCBI Entrez Gene (Gene ID: 5209)].
Gene ID
5209
Gene Name (eCommerce)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene Name (Vector)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene Symbol
PFKFB3
HGNC ID
HGNC:8874
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
Protein Name (eCommerce)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
RefSeq ID
NM_004566
RefSeq Synonyms
NM_004566, NM_001323017, NM_001323016, NM_001314063, NM_001282630, NM_001145443, BC040482,
Research Areas
HIF-1 Signaling,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
PFKFB3 is involved in the synthesis and degradation of fructose 2,6-bisphosphate [taken from NCBI Entrez Gene (Gene ID: 5209)].
UniGene ID
Hs.195471
UniProt ID (eCommerce)
Q16875
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.