human PDLIM1 shRNA silencing AAV

Name 
AAV-h-PDLIM1-shRNA
Cat No 
shAAV-218540
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDLIM1.

shAAV-218540
AAV-h-PDLIM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDLIM1 (PDZ and LIM domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
carboxyl terminal LIM domain protein 1; CLIM1; CLP36; CLP-36; C-terminal LIM domain protein 1; elfin; epididymis secretory protein Li 112; hCLIM1; HEL-S-112; LIM domain protein CLP-36; PDZ and LIM domain protein 1
Description (eCommerce)
CLP36 is a PDZ-domain and LIM-domain containing protein that associates with actin filaments and stress fibers via alpha-actinin. CLP36 has been show to be critical to stress fiber formation and focal adhesions.
Gene ID
9124
Gene Name (eCommerce)
PDZ and LIM domain 1
Gene Name (Vector)
PDZ and LIM domain 1
Gene Symbol
PDLIM1
HGNC ID
HGNC:2067
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
990
ORF Size (bp)
990 bp
Protein Name (eCommerce)
PDZ and LIM domain protein 1
RefSeq ID
NM_020992
RefSeq Synonyms
NM_020992, BC018755, BC000915,
Research Areas
Cytoskeleton,EGFR Signaling,Hypoxia,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
CLP36 is a PDZ-domain and LIM-domain containing protein that associates with actin filaments and stress fibers via alpha-actinin. CLP36 has been show to be critical to stress fiber formation and focal adhesions.
UniGene ID
Hs.368525
UniProt ID (eCommerce)
O00151

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.