human PDLIM1 shRNA silencing AAV

Name 
AAV-h-PDLIM1-shRNA
Cat No 
shAAV-218540
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDLIM1.

shAAV-218540
AAV-h-PDLIM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDLIM1 (PDZ and LIM domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
carboxyl terminal LIM domain protein 1; CLIM1; CLP36; CLP-36; C-terminal LIM domain protein 1; elfin; epididymis secretory protein Li 112; hCLIM1; HEL-S-112; LIM domain protein CLP-36; PDZ and LIM domain protein 1
Description (eCommerce)
CLP36 is a PDZ-domain and LIM-domain containing protein that associates with actin filaments and stress fibers via alpha-actinin. CLP36 has been show to be critical to stress fiber formation and focal adhesions.
Gene ID
9124
Gene Name (eCommerce)
PDZ and LIM domain 1
Gene Name (Vector)
PDZ and LIM domain 1
Gene Symbol
PDLIM1
HGNC ID
HGNC:2067
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
990
ORF Size (bp)
990 bp
Protein Name (eCommerce)
PDZ and LIM domain protein 1
RefSeq ID
NM_020992
RefSeq Synonyms
NM_020992, BC018755, BC000915,
Research Areas
Cytoskeleton,EGFR Signaling,Hypoxia,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
CLP36 is a PDZ-domain and LIM-domain containing protein that associates with actin filaments and stress fibers via alpha-actinin. CLP36 has been show to be critical to stress fiber formation and focal adhesions.
UniGene ID
Hs.368525
UniProt ID (eCommerce)
O00151

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.