human PDK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDK2.
shAAV-218535
AAV-h-PDK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDK2 (pyruvate dehydrogenase kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PDHK2; PDKII
Description (Vector)
PDK2 encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5164
Gene Name (Vector)
pyruvate dehydrogenase kinase 2
Gene Symbol
PDK2
HGNC ID
HGNC:8810
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
RefSeq ID
NM_002611
RefSeq Synonyms
NM_002611, NM_001199900, NM_001199899, NM_001199898, BC063137, BC040478, BC005811,
Species
human
UniGene ID
Hs.256667
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.