human PDE6G shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDE6G.
shAAV-218486
AAV-h-PDE6G-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDE6G (phosphodiesterase 6G). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PDEG; RP57
Description (Vector)
PDE6G encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. PDE6G is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.
Gene ID
5148
Gene Name (Vector)
phosphodiesterase 6G
Gene Symbol
PDE6G
HGNC ID
HGNC:8789
ORF Size (aa)
264
RefSeq ID
NM_002602
RefSeq Synonyms
NM_002602, BC106884,
Species
human
UniGene ID
Hs.654482
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.