human PDC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDC.
shAAV-218430
AAV-h-PDC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDC (phosducin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MEKA; PHD; PhLOP; PhLP
Description (Vector)
PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
5132
Gene Name (Vector)
phosducin
Gene Symbol
PDC
HGNC ID
HGNC:8759
ORF Size (aa)
585
RefSeq ID
NM_002597
RefSeq Synonyms
NM_022576, NM_002597, BC153182, BC148616,
Species
human
UniGene ID
Hs.654381
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.