human PCDH8 shRNA silencing AAV

Name
AAV-h-PCDH8-shRNA

Cat No
shAAV-218331

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PCDH8.

shAAV-218331

AAV-h-PCDH8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PCDH8 (protocadherin 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARCADLIN; PAPC

Description (Vector)

PCDH8 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Gene ID

5100

Gene Name (Vector)

protocadherin 8

Gene Symbol

PCDH8

HGNC ID

HGNC:8660

ORF Size (aa)

3213

ORF Size (bp)

3213 bp

RefSeq ID

NM_002590

RefSeq Synonyms

NM_032949, NM_002590, BC036025,

Species

human

UniGene ID

Hs.19492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.